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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
Postnatal

3 matching records from 3 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Ins2  insulin II   (Synonyms: Ins-2, InsII, Mody, Mody4)
Results  Reference
1J:308553 Akerman I, Maestro MA, De Franco E, Grau V, Flanagan S, Garcia-Hurtado J, Mittler G, Ravassard P, Piemonti L, Ellard S, Hattersley AT, Ferrer J, Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Rep. 2021 Apr 13;35(2):108981
1J:106827 Duvillie B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ, Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin. Endocrinology. 2002 Apr;143(4):1530-7
1J:94589 Lamotte L, Jackerott M, Bucchini D, Jami J, Joshi RL, Deltour L, Knock-in of diphteria toxin A chain gene at Ins2 locus: effects on islet development and localization of Ins2 expression in the brain. Transgenic Res. 2004 Oct;13(5):463-73

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory